Dextro

Contents

Overview of Dextro

  • Dextromethorphan; Morphinan, 3-methoxy-17-methyl-,(9alpha,13alpha,14alpha)-; Romilar (trade); 1,3,4,9,10,10a hexahydro 6methoxy 11 methyl 2h 10,4a iminoethanophenanthrene; arpha; benylin; benylinexpectorant; bexin; calmerphan; calmerphan l; delsym; dextro methorphan; dextro methorphan hydrobromide; dextromethorphan hydrobromide; dextrometorphan; d 3 methoxy n methylmorphinan hydrobromide; doktopectan; dormethan; exseem 12; medicon; mediquell; mediquell cough; methorate; pertussin es; ro 1 5470-5; ro 1 5479; romilar; tussilan; tussilar; Morphinan, 3-methoxy-17-methyl-, (9alpha,13alpha,14alpha)-; 1,3,4,9,10,10a hexahydro 6 methoxy 11 methyl 2h 10,4a iminoethanophenanthrene; benylin expectorant; mediquell cough square
  • Dextromethorphan is available in oral formulation; it’s well absorbed following ingestion with maximum serum concentrations at 2.5 hours.39 The major metabolite of dextromethorphan, dextrorphan, achieves peak plasma concentrations at 1.6 to 1.7 hours following ingestion.40 The volume of distribution of dextromethorphan in humans is not firmly established, but is thought to be large (5.0 to 6.7 L/kg).29 Dextromethorphan and its metabolites undergo renal elimination, with less than 0.1% of the drug being eliminated in the feces.29 The half-life of the parent compound is approximately 2 to 4 hours in individuals with normal metabolism.
  • Dextrose, Cellulose, Liver Meal, Stearic Acid, Ascorbic Acid, dl-Alpha Tocopheryl Acetate, l-Taurine, Natural Flavor, Magnesium Oxide, Choline Bitartrate, Silicon Dioxide, Magnesium Stearate, Ferrous Fumarate, Thiamine Mononitrate, Digestive Enzymes (Aspergillus Niger, Aspergillus Oryzae), d-Calcium Pantothenate, Niacinamide, Inositol, Pyridoxine Hydrochloride, Riboflavin, Grapeseed Extract, Vitamin A Acetate, Niacin, Manganese Sulfate, Chromium Amino Acid Chelate, Selenium Amino Acid Chelate, Zinc Oxide, Potassium Iodide, Biotin, Cyanocobalamin (Vitamin B12 Supplement), Vitamin D3 Supplement, Folic Acid and Copper Sulfate.
  • Dextromethorphan has not been shown to cause vacuolization in animals, also known as Olney’s lesions, despite early speculation that it might, due to similarities with ketamine.[17] In rats,[18] oral administration of dextromethorphan did not cause vacuolization in laboratory tests.[19] Oral administration of dextromethorphan repeatedly during adolescence, however, has been shown to impair learning in those rats during adulthood.[20] The occurrence of Olney’s lesions in humans, however, has not been proven or disproven.
  • Dextro-Transposition of the Great Arteries or d-TGA is a birth defect of the heart in which the two main arteries carrying blood out of the heart – the main pulmonary artery and the aorta – are switched in position, or “transposed.” Because a baby with this defect may need surgery or other procedures soon after birth, d-TGA is considered a critical congenital heart defect (CCHD).
  • Dextro, is officially remixing artists like: George Morel, Chus & Ceballos, Joe T Vannelli, Chus , Richie Santana, Ron Costa, Axel karakasis, Lex Gorrie, Drumcomplex, Insolate, Skober, Cristian Varela, A.Paul, Mendo, Zzino & Guss Carver, John Creamer & Stephane K, Dataworx, Eric Entrena, TKC among others…
  • Dextromethorphan and its metabolites gave a false-positive result for phencyclidine using the ‘instant-view multi-test’ in a urine sample from a 24-month-old girl with ataxia and generalized seizures who had accidentally ingested dextromethorphan; the urine concentration of dextromethorphan was 5.1 mg/l (33A).
  • Dextromethorphan (DXM) is a noncompetitive NMDA-receptor antagonist that acts by reducing excitatory transmission of primary afferent pathways and is effective in managing challenging neuropathic/wind-up pain in patients who, for a variety of reasons, may be unable to receive ketamine.
  • Dextromethorphan’s euphoric effects have a fewtimes been attributed to an increase in dopamine levels, since such an increase generally correlates with pleasurable responses to drugs, as is observed with a few clinical antidepressants, as well as a few recreational drugs.
  • Dextro has releases on a variety of international record labels which include Naked Lunch – BEK Audio – Gynoid – Sleaze – Korpus 9 – Planet Rhythm – Unknown Territory – Odd – Toolroom – Nervous – Stereo – Potobolo – Alleanza – Suara and more!
  • Blockchain

    Dextro Platform is the future of hosting blockchain services.

    Support

    I Have been working with Dextro since 2 years and they are very supportive, they help the candidates to get the project.The Management is very good they motivate the candidates to learn new technologies.

    Do other medications contain dextromethorphan?

    Dextromethorphan can be found alone, as well as in combination with other over the counter medications.Examples of medications that it is frequently found with include: antihistamines, analgesics such as acetaminophen, pseudoephedrine, and expectorants such as guaifenesin.

    Can I take Dextromethorphan (Delsym) if I’m pregnant or breastfeeding?

    Ask a doctor before using this medicine if you are pregnant or breast-feeding.

    Does dextromethorphan interact with my other drugs?

    Enter other medications to view a detailed report.

    Are there any alternatives?

    There are other drugs available to treat your condition.Some may be better suited for you than others.Talk to your doctor about other drug options that may work for you.

    How Is It Taken?

    Products containing dextromethorphan include pills, cough syrups, and liquid cold and flu medications.Dextromethorphan is not snorted through the nostrils or injected, even in its pure powdered form.Over-the-counter cold and flu remedies list all active and inactive ingredients as well as specific dosage charts.Physicians and pharmacists recommend that patients taking liquid medications use precise measuring cups, often provided with the products, rather than teaspoons or tablespoons from a kitchen drawer.If the product does not come with a measuring cup, pharmacies have them in stock and will provide one upon request.

    How should I take dextromethorphan and promethazine?

    Take this medication exactly as it has been prescribed by your doctor.Do not use the medication in larger amounts, or use it for longer than recommended.Follow the directions on your prescription label.Cough or cold medicine is usually taken only for a short time until your symptoms clear up.

    Can I take dextromethorphan if I’m pregnant?

    Dextromethorphan is considered a pregnancy category C drug, which means animal studies have shown that dextromethorphan has bad effects on the animal fetus, but there are no adequate studies in humans.If you are pregnant or are thinking of becoming pregnant, speak with your doctor about the risks and benefits before starting dextromethorphan.

    What drugs and food should I avoid while taking Dextromethorphan (Delsym)?

    Avoid driving or hazardous activity until you know how this medicine will affect you.Your reactions could be impaired.

    How should I take dextromethorphan?

    Use dextromethorphan exactly as directed on the label, or as it has been prescribed by your doctor.Do not use the medication in larger amounts, or use it for longer than recommended.Cough medicine is usually taken only for a short time until your symptoms clear up.

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    How to take Dextromethorphan (Delsym)?

    Use Dextromethorphan (Delsym) exactly as directed on the label, or as prescribed by your doctor.Do not use in larger or smaller amounts or for longer than recommended.

    Can dextromethorphan be abused?

    On the street, dextromethorphan abuse is known as robodosing, robotripping, dexing, and going pharming to name a few.Slang names for dextromethorphan itself include: Dex, DM, Triple C, Skittles, Velvet, and Candy.In high doses, dextromethorphan causes euphoria, hallucinations, and “out of body” experiences, leading to potential abuse.However, in these same doses, dextromethorphan can also be life-threatening (see “What happens if I take too much dextromethorphan?”) and therefore should never be used to get high.The potential for abuse is one of the reasons the tablet form of dextromethorphan is no longer available over the counter.

    How should this medicine be used?

    Dextromethorphan comes as a liquid-filled capsule, a chewable tablet, a dissolving strip, a solution (liquid), an extended-release (long-acting) suspension (liquid), and a lozenge to take by mouth.It is usually taken every 4 to 12 hours as needed.Follow the directions on the package or prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.

    A Mass Effect-inspired question: what are dextro & levo DNA?

    In the Mass Effect series, there are 2 different genetic types described: dextro & levo.Levo-protein DNA is what species like the krogan and humans have, but quarians & turians are dextro-based.

    What is this medicine?

    BROMPHENIRAMINE; DEXTROMETHORPHAN; PSEUDOEPHEDRINE (brome fen IR a meen; dex troe meth OR fan; soo doe e FED rin) is a histamine blocker, cough suppressant, and a decongestant.It can help relieve cough, runny nose, stuffy nose, sneezing, and itchy or watery eyes.This medicine is used to treat allergy and cold symptoms.This medicine will not treat an infection.

    What does my medication look like?

    Dextromethorphan is available over the counter under many different brand and generic names.Ask your pharmacist any questions you have about this medication, especially if it is new to you.

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    Deaths from Over-the-Counter Drugs?

    Since 2000, newspapers and magazines have reported numerous deaths associated with dextromethorphan abuse.A twenty-year-old Colorado man was found dead in his bed of a Coricidin HBP overdose in May of 2004, as reported in the Rocky Mountain News.A few months earlier, People Weekly magazine detailed the similar death of a twenty-two-year-old college honor student who overdosed on powder he bought on the Internet.The same People Weekly article mentioned a fourteen-year-old Colorado boy who was killed by an automobile when trying to cross a busy highway to purchase more pills.

    What are the possible side effects of dextromethorphan and promethazine?

    Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

    Are There Any Medical Reasons for Taking This Substance?

    Dextromethorphan is recommended for quieting coughs.It does not work on the nose or the throat, but rather on the brain and the central nervous system, to lessen the body’s chemical signals to cough.

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    What happens if I miss a dose?

    Since cough and cold medicine is usually taken only as needed, you may not be on a dosing schedule.If you are taking the medication regularly, take the missed dose as soon as you remember.If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time.Do not take extra medicine to make up the missed dose.

    Where should I keep my medicine?

    Keep out of the reach of children.

    What is dextromethorphan?

    Dextromethorphan is a cough suppressant that is used to treat cough caused by the common cold or flu.

    What happens if I overdose?

    Seek emergency medical attention if you think you have used too much of this medicine.

    Can I give dextromethorphan to my child?

    Multiple sources, including the American Academy of Pediatrics and the Food and Drug Administration (FDA), do not recommend using over-the-counter dextromethorphan-containing products in children younger than 4 years of age unless instructed by your child’s healthcare provider.

    What happens if I overdose?

    Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

    Can’t find what you’re looking for?

    All prescription and over-the-counter (OTC) drugs in the U.S.are required by the FDA to have an imprint code.If your pill has no imprint it could be a vitamin, diet, herbal, or energy pill, or an illicit or foreign drug.It is not possible to accurately identify a pill online without an imprint code.

    What Are the Plateaus for Dextromethorphan Overdose?

    As an abused drug, dextromethorphan has been compared to hallucinogens such as ketamine and PCP.Four “plateaus” have been identified for dextromethorphan overdose.Each plateau carries a different set of symptoms and behaviors.The higher the plateau of abuse, the greater the chances of permanent brain damage, psychological addiction, or lasting behavioral problems in the user.

    What happens if I miss a dose?

    Since cough medicine is usually taken only as needed, you may not be on a dosing schedule.If you are taking the medication regularly, take the missed dose as soon as you remember.If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time.Do not take extra medicine to make up the missed dose.

    What is the most important information I should know about dextromethorphan?

    Do not use this medicine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.

    What Is It Made Of?

    Dextromethorphan is a synthetic substance, meaning it is manufactured in a lab.It was first developed by modifying levomethorphan, a non-carbon-containing opioid.While the brain “reads” levomethorphan like an opiate, it does not “read” dextromethorphan the same way.Thus, at recommended doses, dextromethorphan does not cause drowsiness, dizziness, or sedation.

    What is dextro-Transposition of the Great Arteries (d-TGA)?

    Dextro-Transposition of the Great Arteries or d-TGA is a birth defect of the heart in which the two main arteries carrying blood out of the heart – the main pulmonary artery and the aorta – are switched in position, or “transposed.” Because a baby with this defect may need surgery or other procedures soon after birth, d-TGA is considered a critical congenital heart defect (CCHD).Congenital means present at birth.

    What happens if I overdose?

    Seek emergency medical attention if you think you have used too much of this medicine.

    What should I avoid while taking dextromethorphan?

    Avoid driving or hazardous activity until you know how this medicine will affect you.Your reactions could be impaired.

    Are there any reasons I should not take dextromethorphan?

    Because of how it works in the brain, dextromethorphan interacts with many medications, particularly those affecting serotonin (i.e., serotonergic medication).If you are taking serotonergic medications, do not take dextromethorphan.Some serotonergic medications are prescribed for depression or anxiety, but there are many kinds of medications that are serotonergic.Examples of serotonergic medications include but are not limited to: SSRIs (e.g, fluoxetine [Prozac], paroxetine [Paxil]), bupropion (Wellbutrin), TCAs (e.g.amitriptyline [Elavil]), tramadol (Ultram), fentanyl, migraine medications called “triptans,” herbal medications such as St.John’s Wort and Syrian Rue, as well as multiple other nausea medications, pain medications, and some antibiotics.Certain illicit drugs, such as amphetamine, ecstasy (MDMA), and cocaine have been known to interact with dextromethorphan as well.When taken together with these kinds of medications and drugs, dextromethorphan can cause a serious condition known as serotonin syndrome.Symptoms of serotonin syndrome range from a mild tremor to seizures, life threatening hyperthermia (elevated temperature), and shock.Consult your physician before taking dextromethorphan to ensure none of your medications will interact with dextromethorphan to cause this life-threatening reaction.

    What is dextromethorphan and promethazine?

    Dextromethorphan is a cough suppressant.It affects the signals in the brain that trigger cough reflex.

    What special dietary instructions should I follow?

    Unless your doctor tells you otherwise, continue your normal diet.

    What should I avoid?

    Avoid drinking alcohol.It can increase some of the side effects of dextromethorphan.This medication can cause side effects that may impair your thinking or reactions.Be careful if you drive or do anything that requires you to be awake and alert.

    What is the most important information I should know about dextromethorphan?

    Call your doctor immediately if you experience uncontrollable movements of your eyes, lips, tongue, face, arms, or legs.These could be early signs of dangerous side effects.

    What Kind of Drug Is It?

    Dextromethorphan (DXM) is an ingredient in more than 100 over-the-counter (OTC) cold, flu, and cough remedies.It is used specifically to suppress coughs.The drug is widely used in OTC medications because, at normal dosages, it does not produce side effects in most people.Dextromethorphan is a synthetic drug, meaning that it is manufactured in a laboratory.

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    Where can I get more information?

    Your pharmacist can provide more information about dextromethorphan.

    Have you ever purchased Dextro-Tuss GG Syrup?

    This survey is being conducted by the WebMD marketing sciences department.

    What should I avoid while taking dextromethorphan and promethazine?

    This medication can cause side effects that may impair your thinking or reactions.Be careful if you drive or do anything that requires you to be awake and alert.

    What other drugs will affect dextromethorphan?

    Avoid using this medicine with other drugs that cause drowsiness or slow your breathing (such as opioid medicine, a muscle relaxer, or medicine for anxiety or seizures).Ask a doctor or pharmacist before using any other medication, including prescription and over-the-counter medicines, vitamins, and herbal products.Not all possible drug interactions are listed in this medication guide.

    What other information should I know?

    Ask your pharmacist any questions you have about dextromethorphan.

    What if I miss a dose?

    If you miss a dose, take it as soon as you can.If it is almost time for your next dose, take only that dose.Do not take double or extra doses.

    Have you ever purchased Dextromethorphan Hbr Syrup?

    This survey is being conducted by the WebMD marketing sciences department.

    Where can I get more information?

    Your pharmacist has information about dextromethorphan and promethazine written for health professionals that you may read.

    Why is this medication prescribed?

    Dextromethorphan is used to temporarily relieve cough caused by the common cold, the flu, or other conditions.Dextromethorphan will relieve a cough but will not treat the cause of the cough or speed recovery.Dextromethorphan is in a class of medications called antitussives.It works by decreasing activity in the part of the brain that causes coughing.

    What happens if I take too much dextromethorphan?

    The symptoms of dextromethorphan poisoning are dependent on the amount ingested.Symptoms range from feeling more stimulated (lower doses); to euphoria, hallucinations, and out of body experiences (moderately high doses); to coma and even death (extremely high doses).Symptoms begin within a half hour of taking dextromethorphan and can last up to 6 hours or more.Although overdoses usually occur when dextromethorphan is taken at higher than recommended doses, in a small percentage of the population toxicity can occur even at standard or low doses.This group of individuals is referred to as “poor metabolizers,” because they are unable to break down the medication the same way most individuals do.

    How should I take dextromethorphan?

    Use exactly as directed on the label, or as prescribed by your doctor.Cold or cough medicine is only for short-term use until your symptoms clear up.

    What should I watch for while using this medicine?

    Tell your doctor or health care professional if your symptoms do not improve or if they get worse.If you have trouble falling asleep at night, take the last dose of the day at least a few hours before bedtime.

    How should I use this medicine?

    Take this medicine by mouth with a full glass of water.Follow the directions on the prescription label.Use a specially marked spoon or container to measure your medicine.Household spoons are not accurate.Take this medicine with food or milk if it upsets your stomach.Take your doses at regular times.Do not take more medicine than directed.

    What is dextromethorphan?

    Dextromethorphan is an over the counter medication that is chemically similar to some prescription pain medications such as codeine and morphine.Unlike these medications, however, dextromethorphan is used to suppress cough (antitussive) rather than treat pain.It is available as a pill, liquid, oral strip, and lozenge.

    What are the possible side effects of dextromethorphan?

    Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

    What is the most important information I should know about Dextromethorphan (Delsym)?

    Do not use dextromethorphan if you have used an MAO inhibitor in the past 14 days.A dangerous drug interaction could occur.MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

    What happens if I miss a dose?

    Since cough or cold medicine is used when needed, you may not be on a dosing schedule.Skip any missed dose if it’s almost time for your next dose.Do not use two doses at one time.

    What are the side effects of Dextromethorphan (Delsym)?

    Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

    What is brompheniramine-dextromethorphan-pseudoephedrine?

    Brompheniramine-dextromethorphan-pseudoephedrine oral syrup is a prescription drug that’s available as the brand-name drug Bromfed DM.It’s also available as a generic drug.Generic drugs usually cost less than the brand-name version.In some cases, they may not be available in all strengths or forms as the brand-name drug.

    What is dextromethorphan?

    Dextromethorphan is a cough suppressant.It affects the signals in the brain that trigger cough reflex.

    What should I discuss with my healthcare provider before taking dextromethorphan and promethazine?

    Do not use dextromethorphan and promethazine if you have asthma or other lung disease.

    What should I discuss with my healthcare provider before taking dextromethorphan?

    Do not use dextromethorphan if you have used an MAO inhibitor in the past 14 days.A dangerous drug interaction could occur.MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

    What should I do if I forget a dose?

    Dextromethorphan is usually taken as needed.If your doctor has told you to take dextromethorphan regularly, take the missed dose as soon as you remember it.However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule.Do not take a double dose to make up for a missed one.

    What should I know about storage and disposal of this medication?

    Keep this medication in the container it came in, tightly closed, and out of reach of children.Store it at room temperature and away from excess heat and moisture (not in the bathroom).

    What treatment is available for dextromethorphan poisoning?

    Treatment of dextromethorphan poisoning is mainly supportive, meaning a variety of medical options exist for treatment while in the hospital.Some hospital-based treatment options include sedating the patient if they pose a risk to themselves or others; cooling them down if their body temperature is too high; giving them fluids through an IV line if they show signs of severe dehydration; checking the electrolyte levels in the body and ensuring all of them are within a normal and safe range; or potentially placing a breathing tube if they are unable to breathe sufficiently on their own.Often complicating dextromethorphan poisoning is the fact that when patients take it in the combination form, they also overdose on the other medications mixed in with the combination product.In these cases, the appropriate treatment must be given for the other medications that they overdosed on as well.

    History of Dextro

  • In 1935, Dextro Energen was launched in cube form via specialized retailers.
  • In 1949, American chemists applied for a patent on dextromethorphan, after having isolated it from its parent drug, levomethorphan, a synthetic opioid.
  • In 1981, a paper by Gosselin estimated that the lethal dose is between 50 and 500 mg/kg.
  • In 2003, the states of Texas and North Dakota refused to pass legislation that would make the purchase of certain cold products illegal for persons under the age of eighteen.
  • In the 1960s, a dextromethorphan-only pill, Romilar, was introduced as an over-the-counter medication.